SCHEMBL20019403

SCHEMBL20019403

Cc1nc2ccc(-c3ccc(-c4c5c(c(-c6ccccc6)c6ccccc46)=CCCC=5)cc3)cc2n1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 1/20 0.41
AVPR1A P37288 1/20 0.40
CYP1A2 P05177 1/20 0.40
PDE10A Q9Y233 1/20 0.40
HSD17B10 Q99714 2/20 0.39
DCTPP1 Q9H773 1/20 0.39
HCAR1 Q9BXC0 2/20 0.38
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.37
PIK3CA P42336 2/20 0.37
MTOR P42345 2/20 0.37
MEN1 O00255 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
PIK3CD O00329 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19310492 0.89 MAPK1 (0.55) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL17932824 0.89 MAPK1 (0.55) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL21515507 0.85 MAPK1 (0.50) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL1104832 0.84 MAPK1 (0.65) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL24812208 0.83 MAPK1 (0.51) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL22665756 0.83 MAPK1 (0.39) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL25540429 0.83 HTT (0.48) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL24812214 0.81 MAPK1 (0.49) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL19054475 0.80 MAPK1 (0.41) MAPK1HTTALDH1A1AVPR1ACYP1A2
SCHEMBL19310491 0.79 ALDH1A1 (0.58) MAPK1HTTALDH1A1AVPR1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3940805-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS COMPRISING SAME Samsung Display Co., Ltd. (KR) 2022-01-19 EP disclosed
EP-3301097-A2 [1]BENZOTHIENO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) Samsung Display Co., Ltd. (KR) 2018-04-04 EP disclosed