SCHEMBL20019628

SCHEMBL20019628

CN1CCSC12CCCCNC2

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.43
SOS2 Q07890 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15427196 0.95 SOS1 (0.40) SOS1SOS2
SCHEMBL25055400 0.87 SOS1 (0.38) SOS1SOS2
SCHEMBL15478472 0.86 SOS1 (0.39) SOS1SOS2
SCHEMBL14277018 0.80 SOS1 (0.31) SOS1SOS2
SCHEMBL26777987 0.78 SOS1 (0.30) SOS1SOS2
SCHEMBL25055746 0.78
SCHEMBL15478461 0.75 ADRA2C (0.39) SOS1SOS2
SCHEMBL12626920 0.72 ADRA2C (0.31) SOS1SOS2
SCHEMBL12656495 0.72 TSHR (0.33) SOS1SOS2
SCHEMBL20019636 0.72 SOS1 (0.30) SOS1SOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2918587-B1 Filamin A binding compounds and their use as anti-inflammatory and analgesic agents PAIN THERAPEUTICS INC (US) 2018-04-04 EP disclosed