Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12626420 | 0.79 | GPR119 (0.43) | GPR119 | |
| SCHEMBL12626413 | 0.77 | GPR119 (0.38) | GPR119USP2SMN1; SMN2RECQLFAAH | |
| SCHEMBL21551547 | 0.68 | GPR119 (0.52) | GPR119USP2SMN1; SMN2RECQLFAAH | |
| SCHEMBL22799095 | 0.66 | USP2 (0.49) | GPR119USP2SMN1; SMN2RECQLHPGD | |
| SCHEMBL15740834 | 0.66 | USP2 (0.42) | GPR119USP2SMN1; SMN2RECQLHPGD | |
| SCHEMBL1446828 | 0.66 | HPGD (0.43) | GPR119USP2SMN1; SMN2RECQLHPGD | |
| SCHEMBL6152989 | 0.66 | USP2 (0.47) | GPR119USP2SMN1; SMN2RECQLHPGD | |
| SCHEMBL17848671 | 0.66 | USP2 (0.47) | GPR119USP2SMN1; SMN2RECQLHPGD | |
| SCHEMBL12626985 | 0.65 | USP2 (0.40) | GPR119USP2SMN1; SMN2RECQLFAAH | |
| SCHEMBL2997902 | 0.65 | LIMK2 (0.51) | GPR119USP2SMN1; SMN2RECQLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918587-B1 | Filamin A binding compounds and their use as anti-inflammatory and analgesic agents | PAIN THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |