Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20019918 | 0.71 | PTGS2 (0.38) | — | |
| SCHEMBL15787365 | 0.64 | HTR2A (0.38) | HTR2A | |
| SCHEMBL15784847 | 0.62 | HTR2A (0.37) | HTR2A | |
| SCHEMBL900866 | 0.62 | PTGS2 (0.31) | — | |
| SCHEMBL6116944 | 0.62 | CNR1 (0.33) | — | |
| SCHEMBL17015131 | 0.62 | KCNN4 (0.41) | — | |
| SCHEMBL20019823 | 0.61 | HTR2A (0.36) | HTR2A | |
| SCHEMBL6116199 | 0.61 | PDK2 (0.33) | — | |
| SCHEMBL6118269 | 0.60 | PDK2 (0.32) | — | |
| SCHEMBL6116642 | 0.60 | TLR8 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697229-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |