Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301007 | 0.73 | — | — | |
| SCHEMBL3101364 | 0.73 | — | — | |
| SCHEMBL3101358 | 0.73 | — | — | |
| SCHEMBL6724903 | 0.71 | — | — | |
| SCHEMBL2123353 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL28824763 | 0.70 | NPSR1 (0.36) | NPSR1CHRM1 | |
| SCHEMBL24682898 | 0.69 | NPSR1 (0.39) | NPSR1 | |
| SCHEMBL15841044 | 0.68 | CA12 (0.31) | — | |
| SCHEMBL471202 | 0.67 | NPSR1 (0.38) | NPSR1 | |
| SCHEMBL25189500 | 0.67 | NPSR1 (0.38) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627664-B1 | CYCLOSPORIN ANALOGS | ALLERGAN INC (US) | 2018-04-04 | — | — | EP | disclosed |