Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15518193 | 0.98 | TAAR1 (0.52) | TAAR1PNMTSIGMAR1DAOIGF1R | |
| SCHEMBL793707 | 0.88 | TAAR1 (0.69) | TAAR1PNMTSIGMAR1DAOALOX15 | |
| Hydrochloric Acid SCHEMBL3271461 | 0.86 | TAAR1 (0.67) | TAAR1PNMTSIGMAR1DAOALOX15 | |
| SCHEMBL6341558 | 0.84 | TAAR1 (0.53) | TAAR1PNMTSIGMAR1IGF1RALOX15 | |
| SCHEMBL4037320 | 0.83 | PNMT (0.76) | TAAR1PNMTSIGMAR1IGF1RALOX15 | |
| SCHEMBL16954102 | 0.82 | DAO (0.43) | TAAR1PNMTSIGMAR1DAOIGF1R | |
| SCHEMBL79509 | 0.82 | DAO (0.43) | TAAR1PNMTSIGMAR1DAOIGF1R | |
| SCHEMBL80687 | 0.82 | IGF1R (0.44) | TAAR1PNMTSIGMAR1DAOIGF1R | |
| SCHEMBL14671446 | 0.82 | GLA (0.47) | TAAR1PNMTSIGMAR1DAOIGF1R | |
| Hydrochloric Acid SCHEMBL14829816 | 0.82 | PNMT (0.73) | TAAR1PNMTSIGMAR1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697229-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |