SCHEMBL20020162

SCHEMBL20020162

Cc1cc(COc2ccccc2)on1

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
RAB9A P51151 5/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
NPC1 O15118 3/20 0.64
TDP1 Q9NUW8 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
ALDH1A1 P00352 1/20 0.63
MAPT P10636 1/20 0.58
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9500113 0.94 MEN1 (0.65) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL10938471 0.83 MEN1 (0.59) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL4720744 0.83 MEN1 (0.59) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL20020236 0.83 MEN1 (0.59) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL11032320 0.80 MEN1 (0.51) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL9366576 0.77 MEN1 (0.52) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL10938868 0.77 MEN1 (0.52) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL14198666 0.77 RAB9A (0.60) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL3427804 0.76 BCHE (0.62) MEN1KMT2AALDH1A1MAPT
SCHEMBL15932182 0.76 MAPT (0.63) MEN1KMT2ARAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed