Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172117 | 0.84 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL21104226 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL29690366 | 0.81 | TDP1 (0.53) | CYP1A2CYP2C19ALDH1A1HTTTDP1 | |
| SCHEMBL18570412 | 0.81 | TDP1 (0.53) | CYP1A2CYP2C19ALDH1A1HTTTDP1 | |
| SCHEMBL21104793 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL11844469 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL21751760 | 0.78 | ALDH1A1 (0.59) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL110932 | 0.77 | CYP1A2 (0.81) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL6283894 | 0.77 | HTT (0.41) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT | |
| SCHEMBL29708563 | 0.77 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649080-B1 | INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KK (JP) | 2018-04-04 | — | — | EP | disclosed |