Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244312 | 1.00 | PSIP1 (0.49) | PSIP1CYP3A4DHODHFABP3FABP4 | |
| SCHEMBL15182686 | 0.92 | PSIP1 (0.41) | PSIP1CYP3A4DHODHFABP3FABP4 | |
| SCHEMBL241617 | 0.91 | PSIP1 (0.48) | PSIP1CYP3A4DHODHGRM2KDM4E | |
| SCHEMBL247280 | 0.91 | PSIP1 (0.48) | PSIP1CYP3A4DHODHGRM2KDM4E | |
| SCHEMBL244914 | 0.90 | PSIP1 (0.51) | PSIP1CYP3A4DHODHFABP3FABP4 | |
| SCHEMBL244717 | 0.90 | PSIP1 (0.51) | PSIP1CYP3A4DHODHFABP3FABP4 | |
| SCHEMBL243700 | 0.89 | PSIP1 (0.50) | PSIP1CYP3A4DHODHSMN1; SMN2KDM4E | |
| SCHEMBL243122 | 0.88 | PSIP1 (0.49) | PSIP1CYP3A4DHODHFABP3FABP4 | |
| SCHEMBL243123 | 0.88 | PSIP1 (0.49) | PSIP1CYP3A4DHODHFABP3FABP4 | |
| SCHEMBL243291 | 0.87 | PSIP1 (0.48) | PSIP1CYP3A4DHODHGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |