Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944404 | 0.85 | NPC1 (0.46) | NPC1RAB9ALMNAHTTGNE | |
| SCHEMBL2869584 | 0.84 | BPTF (0.50) | — | |
| SCHEMBL11635317 | 0.84 | CYP1A2 (0.51) | CYP1A2NPC1RAB9AHTTCHRM4 | |
| SCHEMBL64557 | 0.83 | NPC1 (0.47) | CYP1A2NPC1RAB9ALMNAHTT | |
| SCHEMBL22557496 | 0.83 | LMNA (0.41) | LMNAHTTCNR2 | |
| SCHEMBL607319 | 0.83 | CNR2 (0.56) | NPC1RAB9ALMNAHTTCNR2 | |
| SCHEMBL2421817 | 0.83 | BPTF (0.56) | CYP1A2LMNAHTTALDH1A1 | |
| SCHEMBL11636961 | 0.82 | CYP1A2 (0.49) | CYP1A2NPC1RAB9ALMNAHTT | |
| SCHEMBL15754487 | 0.81 | LMNA (0.50) | LMNAHTTCNR2 | |
| Hydrochloric Acid SCHEMBL30263381 | 0.81 | CNR2 (0.55) | NPC1RAB9ALMNAHTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925745-B1 | CXCR7 ANTAGONISTS | CHEMOCENTRYX INC (US) | 2018-04-04 | — | — | EP | disclosed |