Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58561 | 0.81 | TSHR (0.49) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| Fluoride SCHEMBL6346 | 0.80 | TSHR (0.47) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL17880662 | 0.77 | TSHR (0.44) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL936121 | 0.77 | TSHR (0.44) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| Fluoride SCHEMBL29274482 | 0.75 | TSHR (0.43) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| Phosphoric Acid SCHEMBL19406123 | 0.73 | HDAC3 (0.42) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL433711 | 0.73 | TSHR (0.50) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL9612373 | 0.73 | TSHR (0.53) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL16497703 | 0.73 | TSHR (0.53) | TSHRNPSR1RXFP1SLC9A1KEAP1 | |
| SCHEMBL448453 | 0.72 | HDAC3 (0.41) | TSHRNPSR1RXFP1SLC9A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094140-A1 | FLUORESCENT DYES AND THEIR USES AS BIOMARKERS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2018-04-05 | — | — | US | disclosed |