Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.40 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | PPP5C | P53041 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503580 | 1.00 | GABRR1 (0.40) | GABRR1GABRR2GRM2PPP5CATM | |
| SCHEMBL11905774 | 1.00 | GABRR1 (0.40) | GABRR1GABRR2GRM2PPP5CATM | |
| SCHEMBL19857434 | 1.00 | GABRR1 (0.40) | GABRR1GABRR2GRM2PPP5CATM | |
| SCHEMBL5500131 | 0.84 | GABRR1 (0.48) | GABRR1GABRR2GRM2PPP5CLMNA | |
| SCHEMBL7722913 | 0.84 | GABRR1 (0.48) | GABRR1GABRR2GRM2PPP5CLMNA | |
| SCHEMBL10441953 | 0.84 | GABRR1 (0.48) | GABRR1GABRR2GRM2PPP5CLMNA | |
| SCHEMBL2869805 | 0.83 | GABRR1 (0.39) | GABRR1GABRR2GRM2PPP5CATM | |
| SCHEMBL17803105 | 0.83 | GABRR1 (0.39) | GABRR1GABRR2GRM2PPP5CATM | |
| SCHEMBL2869807 | 0.83 | GABRR1 (0.39) | GABRR1GABRR2GRM2PPP5CATM | |
| SCHEMBL20625191 | 0.83 | GABRR1 (0.39) | GABRR1GABRR2GRM2PPP5CATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093943-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093943-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | CTRC, HAVCR2, HGFAC | GABRR1 3940/4885GABRR2 4213/4885GRM2 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.