Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.70 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 2/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18163567 | 0.86 | TARBP2 (0.53) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL2485336 | 0.85 | TARBP2 (0.94) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL28295536 | 0.84 | TARBP2 (0.77) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL28295518 | 0.83 | TARBP2 (1.00) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL20022402 | 0.82 | IKBKB (0.58) | TARBP2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4918154 | 0.80 | TARBP2 (1.00) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL17768259 | 0.79 | TARBP2 (0.82) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL7907774 | 0.79 | TARBP2 (0.82) | TARBP2PDCD4KDM4EALDH1A1HPGD | |
| SCHEMBL22436921 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL2112342 | 0.78 | CA1 (0.57) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | TYRO3, MERTK, AXL | TARBP2 3739/4885PDCD4 1289/4885KDM4E 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.