SCHEMBL28295536

SCHEMBL28295536

CCOC(=O)c1nc(-c2ccncc2)oc1C

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 7/20 0.77
PDCD4 Q53EL6 1/20 0.71
HSD17B10 Q99714 2/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 1/20 0.55
KMT2A Q03164 1/20 0.55
CDC7 O00311 6/20 0.51
DBF4 Q9UBU7 6/20 0.51
MAPT P10636 2/20 0.50
ALOX15 P16050 1/20 0.50
GAA P10253 1/20 0.48
POLB P06746 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4918154 0.87 TARBP2 (1.00) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL2485336 0.87 TARBP2 (0.94) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL7907774 0.86 TARBP2 (0.82) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL17768259 0.86 TARBP2 (0.82) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL28295527 0.84 TARBP2 (1.00) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL28295518 0.84 TARBP2 (1.00) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL11623692 0.84 TARBP2 (0.80) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL28297264 0.84 TARBP2 (1.00) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL7699490 0.84 TARBP2 (0.67) TARBP2PDCD4HSD17B10KDM4EALDH1A1
SCHEMBL18004074 0.84 TARBP2 (0.74) TARBP2PDCD4HSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810071-A A kind of miRNA biosynthesis inhibitor 中国科学院成都生物研究所 2019-05-28 CN disclosed