Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 3/20 | 0.56 |
| ▸ | MET | P08581 | 15/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022432 | 0.90 | MET (0.56) | PTK2BMETSYKPTK2AXL | |
| SCHEMBL18163438 | 0.89 | MET (0.56) | PTK2BMETSYKPTK2AXL | |
| SCHEMBL20022454 | 0.88 | MET (0.56) | PTK2BMETSYKPTK2AXL | |
| SCHEMBL20022422 | 0.87 | MET (0.62) | PTK2BMETSYKPTK2AXL | |
| SCHEMBL18163394 | 0.87 | MET (0.56) | PTK2BMETSYKPTK2 | |
| SCHEMBL18163565 | 0.87 | MET (0.56) | PTK2BMETSYKPTK2AXL | |
| SCHEMBL20022425 | 0.87 | MET (0.60) | PTK2BMETSYKPTK2 | |
| SCHEMBL18163518 | 0.86 | MET (0.56) | PTK2BMETSYKPTK2 | |
| SCHEMBL20022475 | 0.86 | MET (0.57) | METSYKAXL | |
| SCHEMBL20022458 | 0.86 | MET (0.58) | PTK2BMETSYKPTK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934274-B2 | Quinoline derivatives as TAM RTK inhibitors | QURIENT CO., LTD. (KR) | 2021-03-02 | — | — | US | disclosed |
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934274-B2 | Quinoline derivatives as TAM RTK inhibitors | TYRO3, MERTK, AXL | PTK2B 28/4885MET 5/4885SYK 18/4885 |
| US-20180093968-A1 | QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS | TYRO3, MERTK, AXL | PTK2B 28/4885MET 5/4885SYK 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.