Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20024779 | 0.97 | SMN1; SMN2 (0.33) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL20029876 | 0.94 | ATM (0.38) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL20029928 | 0.94 | ATM (0.38) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL24388302 | 0.92 | L3MBTL1 (0.37) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL20030036 | 0.92 | ATM (0.37) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL20029875 | 0.91 | PRKDC (0.33) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL24388314 | 0.91 | L3MBTL1 (0.36) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL24778820 | 0.91 | L3MBTL1 (0.36) | TBK1NPY5RPLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL24778827 | 0.91 | ATM (0.36) | TBK1NPY5RSMN1; SMN2LMNACCNE2 | |
| SCHEMBL24746546 | 0.91 | L3MBTL1 (0.38) | SMN1; SMN2LMNACCNE2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519415-B1 | CARBAZOLES WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |
| WO-2018060218-A1 | CARBAZOLES WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | WO | disclosed |