SCHEMBL20024205

SCHEMBL20024205

CC(C)(C)c1cc(CCC(=O)OCC(=O)COCC(COC(=O)CCc2cc(-n3nc4ccccc4n3)c(O)c(C(C)(C)C)c2)OC(=O)CCc2cc(-n3nc4ccccc4n3)c(O)c(C(C)(C)C)c2)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 5/20 0.34
▸ MAOB P27338 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ MAOA P21397 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NTRK1 P04629 1/20 0.33
▸ NPC1 O15118 3/20 0.32
▸ RAB9A P51151 3/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ ACHE P22303 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ HTT P42858 2/20 0.31
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20024199 0.90 GAA (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL20024200 0.89 GAA (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL23436513 0.85 GAA (0.31) GAAMAOBKMT2AMAOAMEN1
SCHEMBL9871543 0.84 GAA (0.39) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10470534 0.83 GAA (0.38) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10135978 0.83 ALOX5 (0.44) GAAMAOBKMT2AMAOAMEN1
SCHEMBL9228170 0.82 MAOB (0.34) GAAMAOBKMT2AMAOAMEN1
SCHEMBL100357 0.82 ALOX5 (0.42) GAAMAOBKMT2AMAOAMEN1
SCHEMBL16623979 0.82 ALOX5 (0.42) GAAMAOBKMT2AMAOAMEN1
SCHEMBL10472259 0.82 GAA (0.37) GAAMAOBKMT2AMAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180092819-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION KENVUE BRANDS LLC 2018-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180092819-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION ERCC4, ERCC5, ERCC1 GAA 2391/4885MAOB 1649/4885KMT2A 4518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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