Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18761624 | 0.86 | SLC7A5 (0.37) | GLSKDM4ETLR2TLR1TDP1 | |
| SCHEMBL20025206 | 0.84 | CYP4F2 (0.43) | GLSTLR2TLR1TDP1 | |
| SCHEMBL20025238 | 0.84 | PDK1 (0.36) | GLSTLR2TLR1TDP1 | |
| SCHEMBL18761961 | 0.83 | SLC7A5 (0.34) | GLSKMT2ATLR2TLR1TDP1 | |
| SCHEMBL18741366 | 0.83 | AKT1 (0.34) | GLSTLR2TLR1TDP1 | |
| SCHEMBL18741356 | 0.83 | AKT1 (0.37) | GLSTLR2TLR1TDP1 | |
| SCHEMBL20025235 | 0.83 | SLC7A5 (0.34) | GLSTLR2TLR1TDP1 | |
| SCHEMBL25496280 | 0.81 | TYR (0.45) | CA12CA1CA7CA14 | |
| SCHEMBL30074311 | 0.81 | TYR (0.45) | CA12CA1CA7CA14 | |
| SCHEMBL13225854 | 0.81 | FFAR4 (0.41) | ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059537-A1 | DIAZASPIRO[5.5]UNDECANE DERIVATIVE AND USE THEREOF | 四川海思科制药有限公司 | 2018-04-05 | — | — | WO | disclosed |