Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19989562 | 0.92 | MAPK1 (0.42) | MAPK1DRD2DRD4DRD3PPARG | |
| SCHEMBL19989661 | 0.89 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL19989583 | 0.89 | MAPK1 (0.40) | MAPK1DRD2DRD4DRD3PPARG | |
| SCHEMBL20025216 | 0.88 | MAPK1 (0.46) | MAPK1DRD2DRD4DRD3PPARG | |
| SCHEMBL23735030 | 0.83 | DRD2 (0.45) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735068 | 0.81 | DRD2 (0.43) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL19989629 | 0.81 | MEN1 (0.35) | MAPK1DRD2DRD4DRD3PPARG | |
| SCHEMBL23734851 | 0.81 | DRD2 (0.45) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL20025239 | 0.80 | DRD2 (0.38) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL20025573 | 0.79 | MAPK1 (0.47) | MAPK1DRD2DRD4DRD3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018062924-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG-A ST CO., LTD. (KR) | 2018-04-05 | — | — | WO | disclosed |