Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590043 | 0.85 | GAA (0.47) | CA12CA1CA2CA9GAA | |
| SCHEMBL2879979 | 0.81 | GAA (0.45) | CA12CA1CA2CA9GAA | |
| SCHEMBL70011 | 0.80 | GAA (0.58) | CA12CA1CA2CA9GAA | |
| SCHEMBL17010320 | 0.80 | ABL1 (0.46) | CA12CA1CA2CA9GAA | |
| SCHEMBL30833246 | 0.79 | PDGFRB (0.42) | CA12CA1CA2CA9GAA | |
| SCHEMBL29169382 | 0.79 | PDGFRB (0.42) | CA12CA1CA2CA9GAA | |
| SCHEMBL7863946 | 0.79 | GAA (0.50) | CA12CA1CA2CA9GAA | |
| SCHEMBL25304317 | 0.79 | MAPT (0.45) | CA12CA1CA2CA9GAA | |
| SCHEMBL23774898 | 0.79 | GAA (0.54) | GAAABL1MEN1LMNAKMT2A | |
| SCHEMBL2880424 | 0.79 | GAA (0.42) | CA12CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018060140-A1 | MICROBIOCIDAL BENZOXABOROLES DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-05 | — | — | WO | disclosed |