SCHEMBL30833246

SCHEMBL30833246

COC(=O)c1cc(S)c(C)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.42
FGFR1 P11362 1/20 0.42
PDGFRA P16234 1/20 0.42
FLT1 P17948 1/20 0.42
FGFR3 P22607 1/20 0.42
KDR P35968 1/20 0.42
KDM4E B2RXH2 4/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 3/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GLA P06280 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29169382 1.00 PDGFRB (0.42) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL3187202 0.85 KDM4E (0.48) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL2880424 0.83 GAA (0.42) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL2880073 0.83 NOTUM (0.41) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL3207481 0.83 MAPT (0.47) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL2430255 0.83 KDM4E (0.50) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL28759908 0.81 CA12 (0.47) KDM4EHPGDHSD17B10MAPTGAA
SCHEMBL20027428 0.79 CA12 (0.46) KDM4EMAPTGAAALDH1A1CA12
SCHEMBL3198146 0.79 KDM4E (0.47) PDGFRBFGFR1PDGFRAFLT1FGFR3
SCHEMBL23914174 0.78 MAPT (0.43) KDM4EHPGDHSD17B10MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658749-B Method for preparing aryl carboxylic acid by reacting copper compound catalyzed aryl sulfonium salt with carbon dioxide NANKAI UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-117658749-A Method for preparing aryl carboxylic acid by reacting copper compound catalyzed aryl sulfonium salt with carbon dioxide 南开大学 2024-03-08 CN disclosed