Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679748 | 1.00 | USP30 (1.00) | USP30 | |
| SCHEMBL29679891 | 1.00 | USP30 (1.00) | USP30 | |
| SCHEMBL20028882 | 1.00 | USP30 (1.00) | USP30 | |
| SCHEMBL29679586 | 0.86 | USP30 (1.00) | USP30 | |
| SCHEMBL21145344 | 0.86 | USP30 (1.00) | USP30 | |
| SCHEMBL20028996 | 0.86 | USP30 (1.00) | USP30 | |
| SCHEMBL21145357 | 0.86 | USP30 (1.00) | USP30 | |
| SCHEMBL20028890 | 0.86 | USP30 (1.00) | USP30 | |
| SCHEMBL29679542 | 0.86 | USP30 (1.00) | USP30 | |
| SCHEMBL29679684 | 0.86 | USP30 (1.00) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519397-B1 | CYANO-SUBTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 | MISSION THERAPEUTICS LTD (GB) | 2021-05-19 | — | — | EP | disclosed |
| WO-2018060691-A1 | CYANO-SUBTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 | MISSION THERAPEUTICS LIMITED (GB) | 2018-04-05 | — | — | WO | disclosed |