SCHEMBL29679684

SCHEMBL29679684

N#Cc1cccc(-c2ccc3oc([C@@]4(F)CCCN(C#N)C4)nc3c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20028890 1.00 USP30 (1.00) USP30
SCHEMBL21145357 1.00 USP30 (1.00) USP30
SCHEMBL29679542 1.00 USP30 (1.00) USP30
SCHEMBL21167165 0.88 USP30 (1.00) USP30
SCHEMBL20028843 0.88 USP30 (1.00) USP30
SCHEMBL20028882 0.86 USP30 (1.00) USP30
SCHEMBL29679748 0.86 USP30 (1.00) USP30
SCHEMBL20028883 0.86 USP30 (1.00) USP30
SCHEMBL29679891 0.86 USP30 (1.00) USP30
SCHEMBL20029005 0.84 USP30 (1.00) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 CN claimed
CN-109790148-B Cyano-substituted heterocycles having USP30 inhibitor activity 特殊治疗有限公司 2022-06-07 CN disclosed