Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MDH1 | P40925 | 1/20 | 0.32 |
| ▸ | MDH2 | P40926 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030543 | 0.85 | ALDH1A1 (0.35) | KDM4EHTTKMT2AALDH1A1MEN1 | |
| SCHEMBL20030319 | 0.84 | — | — | |
| SCHEMBL20030317 | 0.83 | CNR2 (0.39) | RECQLHDAC3HDAC1 | |
| SCHEMBL20031372 | 0.77 | NPC1 (0.43) | KDM4EKMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20030557 | 0.76 | CHEK1 (0.40) | KDM4EHTTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20030504 | 0.73 | AAK1 (0.45) | KDM4EALDH1A1GAA | |
| SCHEMBL15156354 | 0.69 | KDM4E (0.49) | KDM4EHTTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20030608 | 0.69 | MYC (0.34) | HTTKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5558290 | 0.68 | KDM4E (0.43) | KDM4EHTTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20030609 | 0.68 | CNR2 (0.38) | HTTKMT2ASMN1; SMN2MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018060072-A1 | NEW SUBSTITUTED BENZIMIDAZOLES, METHODS FOR THE PRODUCTION OF SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAME, AND USE OF SAME TO PRODUCE DRUGS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |