Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030761 | 0.92 | KDM4E (0.36) | SMN1; SMN2KDM4ETDP1L3MBTL1HPGD | |
| SCHEMBL20030978 | 0.88 | — | — | |
| SCHEMBL20030832 | 0.84 | KDM4E (0.40) | SMN1; SMN2KDM4ETDP1L3MBTL1HPGD | |
| SCHEMBL31114900 | 0.83 | PDE10A (0.33) | PPARA | |
| SCHEMBL31114884 | 0.83 | PDE10A (0.33) | PPARA | |
| SCHEMBL20030481 | 0.83 | PTGDR2 (0.35) | KDM4EMEN1KMT2AALDH1A1PPARA | |
| SCHEMBL20030856 | 0.82 | CNR1 (0.38) | SMN1; SMN2KDM4ETDP1L3MBTL1HPGD | |
| SCHEMBL20030760 | 0.81 | PPARA (0.31) | PPARA | |
| SCHEMBL20030930 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ETDP1L3MBTL1HPGD | |
| SCHEMBL20030918 | 0.80 | KDM4E (0.39) | SMN1; SMN2KDM4ETDP1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064080-A1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2018-04-05 | — | — | WO | disclosed |