Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030991 | 0.82 | MAPT (0.34) | KDM4ETDP1MAPTMEN1KMT2A | |
| SCHEMBL31114910 | 0.82 | MAPT (0.34) | KDM4ETDP1MAPTMEN1KMT2A | |
| SCHEMBL20030864 | 0.81 | KDM4E (0.42) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL20031011 | 0.80 | KDM4E (0.38) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL20030973 | 0.79 | KDM4E (0.43) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL19906180 | 0.79 | PTGDR2 (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20030734 | 0.79 | KDM4E (0.36) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL20030870 | 0.78 | KDM4E (0.36) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL15332942 | 0.78 | KDM4E (0.48) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL19905978 | 0.78 | PTGDR2 (0.40) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064080-A1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2018-04-05 | — | — | WO | disclosed |