Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 4/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031433 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20031051 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL6749254 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL30598863 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL12620805 | 0.92 | NR1H2 (0.57) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL24740662 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL904134 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL4409452 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20936755 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20566533 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |