Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 4/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031433 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20031051 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20031049 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL30598863 | 1.00 | NR1H2 (0.60) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL12620805 | 0.92 | NR1H2 (0.57) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL24740662 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL904134 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL4409452 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20936755 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP | |
| SCHEMBL20566533 | 0.90 | NR1H2 (0.68) | NR1H2CHRM2CHRM1CHRM3PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-117377675-A | Bruton's tyrosine kinase degradation agent containing parallel ring or spiro ring | 正大天晴药业集团股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-3312164-B1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES LLC (US) | 2020-12-09 | — | — | EP | disclosed |
| US-20190002452-A1 | FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD. (CN) | 2019-01-03 | — | — | US | disclosed |
| EP-3401315-A1 | FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | Guangzhou Henovcom Bioscience Co. Ltd. (CN) | 2018-11-14 | — | — | EP | disclosed |
| EP-3312164-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | Calitor Sciences, LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-3122729-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | Calitor Sciences, LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| CN-103304552-B | Substituted pyridine compounds and using method thereof and purposes | 广东东阳光药业有限公司 | 2016-12-28 | — | — | CN | disclosed |
| US-9403801-B2 | Substituted heteroaryl compounds and methods of use | CALITOR SCIENCES, LLC (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150274704-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-01 | — | — | US | disclosed |
| WO-2015148867-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-10-01 | — | — | WO | disclosed |
| WO-2013138210-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE | XI NING (US) | 2013-09-19 | — | — | WO | disclosed |
| CN-103304552-A | Substituted pyridine compounds, methods of use and uses thereof | GUANGDONG HEC PHARMACEUTICAL | 2013-09-18 | — | — | CN | disclosed |
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002452-A1 | FXR RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | NR1H4, FXR1, GPBAR1 | NR1H2 6/4885CHRM2 1681/4885CHRM1 1576/4885 |
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | NR1H2 301/4885CHRM2 1292/4885CHRM1 765/4885 |
| US-20150274704-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | PRKACA, PRKDC, PRKACB | NR1H2 976/4885CHRM2 4058/4885CHRM1 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.