Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704386 | 1.00 | NCF1 (0.34) | NCF1SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL20031461 | 1.00 | NCF1 (0.34) | NCF1SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL3439653 | 0.91 | NCF1 (0.32) | NCF1SIGMAR1 | |
| SCHEMBL22704393 | 0.91 | NCF1 (0.32) | NCF1SIGMAR1 | |
| SCHEMBL25645505 | 0.91 | NCF1 (0.32) | NCF1SIGMAR1 | |
| SCHEMBL29340109 | 0.91 | NCF1 (0.32) | NCF1SIGMAR1 | |
| SCHEMBL24697015 | 0.88 | NCF1 (0.33) | NCF1SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL16392548 | 0.88 | NCF1 (0.33) | NCF1SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL2666523 | 0.87 | — | — | |
| SCHEMBL25125458 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230627-A2 | INHIBITORS OF THE MENIN-MLL INTERACTION | Vitae Pharmaceuticals, LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-3174879-B1 | SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2018-07-18 | — | — | EP | disclosed |
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |