SCHEMBL20031862

SCHEMBL20031862

CCC(N)(CC)Cc1ncccc1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
PLAU P00749 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
CXCR4 P61073 3/20 0.35
P2RX7 Q99572 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.33
DAO P14920 1/20 0.33
SSTR4 P31391 1/20 0.33
ADORA2A P29274 3/20 0.33
ADORA1 P30542 1/20 0.33
PDK2 Q15119 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19214821 0.84 NOS3 (0.41) NOS3NOS1NOS2PLAUSMN1; SMN2
SCHEMBL7140521 0.83 NOS3 (0.47) NOS3NOS1NOS2PLAUSMN1; SMN2
SCHEMBL2083712 0.83 NOS3 (0.40) NOS3NOS1NOS2PLAUCXCR4
SCHEMBL19214826 0.81 NOS3 (0.45) NOS3NOS1NOS2PLAUCXCR4
SCHEMBL2083047 0.80 CXCR4 (0.42) NOS3NOS1NOS2PLAUCXCR4
SCHEMBL2084776 0.78 CXCR4 (0.38) NOS3NOS1NOS2PLAUSMN1; SMN2
SCHEMBL10190919 0.77 NOS3 (0.43) NOS3NOS1NOS2PLAUSMN1; SMN2
SCHEMBL91425 0.74
SCHEMBL825251 0.73 NOS3 (0.38) NOS3NOS1NOS2PLAUCXCR4
SCHEMBL29505865 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed