SCHEMBL20031866

SCHEMBL20031866

CCC[C@@H](Cc1cccc(C)n1)Nc1cc(C(C)(C)C)cc(C(C)(C)C)c1O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.37
CYP2C19 P33261 3/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.37
TSHR P16473 1/20 0.37
NR5A2 O00482 1/20 0.33
NR5A1 Q13285 1/20 0.33
HSP90AA1 P07900 1/20 0.32
CRHR1 P34998 1/20 0.31
MEN1 O00255 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
KMT2A Q03164 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
TP53 P04637 1/20 0.30
CYP2D6 P10635 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18157984 0.82 CYP3A4 (0.36) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL20661546 0.82 NR5A2 (0.35) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL18160752 0.78 CYP3A4 (0.38) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL20661547 0.75 CYP3A4 (0.44) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL18593372 0.66 CYP1A2 (0.42) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL18157965 0.63 GAA (0.39) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL23153062 0.63 CCR1 (0.38) MEN1OPRM1OPRD1KMT2A
SCHEMBL20661480 0.62 KDM4E (0.39) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL20024584 0.62 GAA (0.52) CYP2C9CYP2C19CYP3A4CYP1A2TSHR
SCHEMBL23793643 0.62 CA2 (0.46) CYP2C9CYP2C19CYP3A4CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed