Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332647 | 0.98 | MAPT (0.68) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL13721594 | 0.98 | MAPT (0.68) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL6018398 | 0.95 | MAPT (0.77) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL1791955 | 0.94 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL225009 | 0.94 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL431397 | 0.94 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL8962930 | 0.94 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL4815928 | 0.92 | MAPT (0.77) | MAPTRAB9ACYP4A11CYP4F2RARB | |
| SCHEMBL223429 | 0.90 | MAPT (0.79) | MAPTRAB9ACYP4A11CYP4F2POLB | |
| SCHEMBL7321276 | 0.89 | MAPT (0.72) | MAPTRAB9ARARBL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9939555-B2 | Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof | DIC CORPORATION (JP) | 2018-04-10 | — | — | US | disclosed |