Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225009 | 1.00 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL8962930 | 1.00 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL1791955 | 1.00 | MAPT (0.74) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL6018398 | 0.98 | MAPT (0.77) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL7332647 | 0.95 | MAPT (0.68) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL13721594 | 0.95 | MAPT (0.68) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL20032702 | 0.94 | MAPT (0.70) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL223429 | 0.93 | MAPT (0.79) | MAPTRAB9ACYP4A11CYP4F2GAA | |
| SCHEMBL5054312 | 0.93 | MAPT (0.85) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL7908139 | 0.93 | MAPT (0.64) | MAPTRAB9ACYP4A11CYP4F2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113548964-A | Synthetic method of liquid crystal intermediate | 西安淳甄新材料有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113548964-A | Synthetic method of liquid crystal intermediate | 西安淳甄新材料有限公司 | 2021-10-26 | — | — | CN | disclosed |
| EP-2222740-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2017-10-11 | — | — | EP | disclosed |
| EP-2222740-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2017-10-11 | — | — | EP | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-8613868-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC (US) | 2013-12-24 | — | — | US | disclosed |
| WO-2013022610-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
| US-20120021144-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| EP-2222740-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080147-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080147-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021144-A1 | MESOGENIC STABILIZERS | C1S, C5, CCNL2 | MAPT 1278/4885RAB9A 3799/4885CYP4A11 2620/4885 |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ETV6, TERB1, VCL | MAPT 42/4885RAB9A 1297/4885CYP4A11 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.