Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307419 | 0.91 | FFAR4 (1.00) | FFAR4LMNAERCC1ERCC4 | |
| SCHEMBL19307420 | 0.91 | FFAR4 (1.00) | FFAR4LMNAERCC1ERCC4 | |
| SCHEMBL20032807 | 0.84 | FFAR4 (0.81) | FFAR4 | |
| SCHEMBL19307396 | 0.74 | FFAR4 (1.00) | FFAR4 | |
| SCHEMBL20032812 | 0.74 | FFAR4 (0.81) | FFAR4 | |
| SCHEMBL19307397 | 0.74 | FFAR4 (1.00) | FFAR4 | |
| SCHEMBL20032746 | 0.73 | FFAR4 (0.83) | FFAR4 | |
| SCHEMBL20032770 | 0.73 | FFAR4 (0.83) | FFAR4 | |
| SCHEMBL20032811 | 0.73 | FFAR4 (0.83) | FFAR4 | |
| SCHEMBL15021326 | 0.69 | ERCC1 (0.52) | FFAR4LMNAERCC1ERCC4METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938222-B2 | Cyclopropanecarboxylic acid GPR120 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-10 | — | — | US | disclosed |