Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19698251 | 1.00 | TSHR (0.31) | TSHRGAA | |
| SCHEMBL19698594 | 0.98 | RECQL (0.30) | TSHR | |
| SCHEMBL19698244 | 0.98 | RECQL (0.30) | TSHR | |
| SCHEMBL19703734 | 0.94 | TSHR (0.33) | TSHR | |
| SCHEMBL19704337 | 0.94 | TSHR (0.33) | TSHR | |
| SCHEMBL20033247 | 0.92 | SIGMAR1 (0.32) | — | |
| SCHEMBL19698252 | 0.92 | SIGMAR1 (0.32) | — | |
| SCHEMBL19698247 | 0.90 | SIGMAR1 (0.30) | — | |
| SCHEMBL19698595 | 0.90 | SIGMAR1 (0.30) | — | |
| SCHEMBL19698223 | 0.89 | GAA (0.33) | TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938323-B2 | Amatoxin derivatives and conjugates thereof as inhibitors of RNA polymerase | NOVARTIS AG (CH) | 2018-04-10 | — | — | US | disclosed |