Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468345 | 0.85 | EPHX2 (0.40) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E | |
| SCHEMBL12763808 | 0.82 | PIK3CD (0.39) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E | |
| SCHEMBL16440316 | 0.82 | EPHX2 (0.48) | ALDH1A1MAPK1NAMPTKDM4ESMN1; SMN2 | |
| SCHEMBL25724268 | 0.79 | PIK3CD (0.37) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E | |
| SCHEMBL13496818 | 0.79 | PIK3CD (0.43) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E | |
| SCHEMBL9009588 | 0.79 | EPHX2 (0.39) | ALDH1A1MAPK1NAMPTKDM4EHPGD | |
| SCHEMBL25594217 | 0.78 | PIK3CD (0.38) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E | |
| SCHEMBL16160775 | 0.78 | PIK3CD (0.38) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E | |
| SCHEMBL18184074 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL13407587 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPK1PIK3CDNAMPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938234-B2 | PPAR agonists | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2018-04-10 | — | — | US | disclosed |