Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20034420 | 0.88 | GLS (0.55) | GLS | |
| SCHEMBL20034389 | 0.85 | GLS (0.58) | GLS | |
| SCHEMBL19920118 | 0.82 | GLS (0.57) | GLS | |
| SCHEMBL20034353 | 0.82 | GLS (0.56) | GLS | |
| SCHEMBL14986989 | 0.69 | GLS (1.00) | GLS | |
| SCHEMBL19754336 | 0.65 | GLS (0.77) | GLS | |
| SCHEMBL15042300 | 0.65 | GLS (0.73) | GLS | |
| SCHEMBL16305181 | 0.65 | GLS (0.89) | GLS | |
| SCHEMBL18122469 | 0.65 | GLS (0.70) | GLS | |
| SCHEMBL14987534 | 0.64 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938267-B2 | Heterocyclic inhibitors of glutaminase | CALITHERA BIOSCIENCES, INC. (US) | 2018-04-10 | — | — | US | disclosed |