Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20034403 | 0.75 | GLS (0.48) | GLSKAT8 | |
| SCHEMBL15043787 | 0.69 | GLS (0.57) | GLS | |
| SCHEMBL14987548 | 0.66 | GLS (0.62) | GLS | |
| SCHEMBL20034437 | 0.66 | GLS (0.49) | GLSKAT8 | |
| SCHEMBL20034496 | 0.65 | GLS (0.54) | GLSKAT8 | |
| SCHEMBL20034327 | 0.64 | GLS (0.49) | GLSKAT8 | |
| SCHEMBL14987021 | 0.62 | GLS (0.42) | GLS | |
| SCHEMBL14987005 | 0.61 | GLS (0.54) | GLS | |
| SCHEMBL19920325 | 0.61 | GLS (0.68) | GLS | |
| SCHEMBL14987158 | 0.60 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938267-B2 | Heterocyclic inhibitors of glutaminase | CALITHERA BIOSCIENCES, INC. (US) | 2018-04-10 | — | — | US | disclosed |