Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 4/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | CTPS1 | P17812 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129343 | 0.88 | MAP2K1 (0.36) | BRAFKITKCNH2 | |
| SCHEMBL20034598 | 0.84 | MRGPRX1 (0.39) | MRGPRX1HRH1BRAFHSD17B1HSD17B2 | |
| SCHEMBL19367004 | 0.81 | MAPT (0.32) | MAPTKCNH2SCN5A | |
| SCHEMBL15129480 | 0.81 | MAP2K1 (0.33) | BRAF | |
| SCHEMBL391647 | 0.80 | MRGPRX1 (0.44) | MRGPRX1HRH1BRAFHSD17B1HSD17B2 | |
| SCHEMBL20034585 | 0.78 | MRGPRX1 (0.39) | MRGPRX1HRH1BRAFKITPIK3C3 | |
| SCHEMBL20034606 | 0.77 | MAP2K1 (0.49) | MAPTSCN5A | |
| SCHEMBL19050669 | 0.76 | MRGPRX1 (0.40) | MRGPRX1HRH1BRAFHSD17B1HSD17B2 | |
| SCHEMBL12407095 | 0.75 | MRGPRX1 (0.51) | MRGPRX1HRH1BRAFKITKMT2A | |
| SCHEMBL19050690 | 0.75 | MRGPRX1 (0.41) | MRGPRX1HRH1BRAFHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937158-B2 | Benzoheterocyclic compounds and use thereof | SHANGHAI KECHOW PHARMA, INC. (CN) | 2018-04-10 | — | — | US | disclosed |