Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21466334 | 0.93 | GLS (0.83) | GLS | |
| SCHEMBL15042387 | 0.91 | GLS (1.00) | GLS | |
| SCHEMBL14987349 | 0.91 | GLS (1.00) | GLS | |
| SCHEMBL19920110 | 0.90 | GLS (0.83) | GLS | |
| SCHEMBL22623416 | 0.87 | GLS (0.83) | GLS | |
| SCHEMBL21466330 | 0.87 | GLS (0.81) | GLS | |
| SCHEMBL14987711 | 0.85 | GLS (1.00) | GLS | |
| SCHEMBL19920396 | 0.85 | GLS (0.84) | GLS | |
| SCHEMBL15043829 | 0.85 | GLS (1.00) | GLS | |
| SCHEMBL15042473 | 0.85 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938267-B2 | Heterocyclic inhibitors of glutaminase | CALITHERA BIOSCIENCES, INC. (US) | 2018-04-10 | — | — | US | disclosed |