SCHEMBL20036256

SCHEMBL20036256

CCc1c2ccoc2cc2oc(=O)ccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
CYP3A4 P08684 2/20 0.64
CYP2A6 P11509 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
MAPT P10636 1/20 0.64
HPGD P15428 1/20 0.64
KDM4E B2RXH2 3/20 0.63
CYP1B1 Q16678 2/20 0.63
KCNA2 P16389 2/20 0.63
CYP1A1 P04798 1/20 0.63
CYP1A2 P05177 1/20 0.63
PGR P06401 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
CYP2D6 P10635 1/20 0.63
CYP2C9 P11712 1/20 0.63
TSHR P16473 1/20 0.63
MAOA P21397 1/20 0.63
CYP2C19 P33261 1/20 0.63
HSD17B10 Q99714 1/20 0.63
KCNA3 P22001 13/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22361197 0.85 ALDH1A1 (0.66) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
SCHEMBL6991733 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
Hydrochloric Acid SCHEMBL6999089 0.83 ALDH1A1 (0.62) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
SCHEMBL6802035 0.81 ALDH1A1 (0.70) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
SCHEMBL9122678 0.80 ALDH1A1 (0.71) ALDH1A1CYP3A4CYP2A6L3MBTL1KDM4E
Bergaptol SCHEMBL194016 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
Bergaptol SCHEMBL31097369 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
Bergapten SCHEMBL50066 0.77 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
Bergapten SCHEMBL4731782 0.77 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT
Bergapten SCHEMBL29529284 0.77 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2A6L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2954037-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2018-04-11 EP disclosed