Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16995107 | 0.89 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL17001528 | 0.86 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL16995129 | 0.78 | DPP4 (0.48) | P2RX7 | |
| SCHEMBL20036491 | 0.75 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL16995100 | 0.68 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL16995110 | 0.65 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL16995131 | 0.63 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL16995105 | 0.63 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL16462110 | 0.62 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL16995104 | 0.62 | P2RX7 (0.54) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102573-B1 | SUBSTITUTED THIAZOLE OR OXAZOLE P2X7 RECEPTOR ANTAGONISTS | AXXAM SPA (IT) | 2018-04-11 | — | — | EP | disclosed |