Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19731926 | 0.84 | LMNA (0.39) | CNR1CNR2ALOX5POLBTLR7 | |
| SCHEMBL27742972 | 0.80 | NPC1 (0.51) | CNR1CNR2ALOX5POLBTLR7 | |
| SCHEMBL2503008 | 0.80 | POLB (0.38) | POLBNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL27795718 | 0.79 | CNR1 (0.44) | CNR1CNR2ALOX5POLBTLR7 | |
| SCHEMBL17112756 | 0.78 | MEN1 (0.45) | CNR1CNR2ALOX5NPC1RAB9A | |
| SCHEMBL19226006 | 0.78 | CNR1 (0.38) | CNR1CNR2ALOX5POLBTLR7 | |
| SCHEMBL27854827 | 0.78 | CNR1 (0.43) | CNR1CNR2ALOX5POLBTLR7 | |
| SCHEMBL31537082 | 0.78 | CYP1A2 (0.49) | POLBNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL19731925 | 0.78 | MIF (0.46) | CNR1CNR2ALOX5POLBTLR7 | |
| SCHEMBL2364213 | 0.76 | NPC1 (0.53) | CNR1CNR2ALOX5POLBTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509595-B1 | INHIBITORS OF HEMOPOIETIC CELL KINASE (P59-HCK) AND THEIR USE IN THE TREATMENT OF INFLUENZA INFECTION | RESPIVERT LTD (GB) | 2018-04-11 | — | — | EP | disclosed |