Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | CDK4 | P11802 | 5/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038053 | 0.83 | HRH4 (0.41) | OGAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL20255432 | 0.82 | HRH4 (0.39) | OGAMEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL20249432 | 0.80 | HRH4 (0.37) | OGAMEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL21917399 | 0.77 | TRPV1 (0.48) | — | |
| SCHEMBL25106007 | 0.75 | CYP1A2 (0.57) | OGASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL3826525 | 0.74 | LMNA (0.43) | OGAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3828733 | 0.74 | CYP1A2 (0.46) | OGAMEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL25104869 | 0.74 | HRH4 (0.37) | OGAHRH3HRH4 | |
| SCHEMBL31713990 | 0.74 | HRH4 (0.37) | OGAHRH3HRH4 | |
| SCHEMBL31714098 | 0.74 | HRH4 (0.37) | OGAHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |