Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038507 | 0.81 | CXCR4 (0.44) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL22642421 | 0.78 | CXCR4 (0.47) | CXCR4SIGMAR1CHRM2MEN1KMT2A | |
| SCHEMBL20255286 | 0.77 | CXCR4 (0.43) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL20249430 | 0.76 | CXCR4 (0.40) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL20160684 | 0.72 | CXCR4 (0.49) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL3148862 | 0.71 | CXCR4 (0.50) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL32667730 | 0.71 | CYP11B1 (0.51) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL211045 | 0.70 | HRH3 (0.44) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL3065752 | 0.69 | CXCR4 (0.45) | CXCR4KDM5CKDM4CSIGMAR1LMNA | |
| SCHEMBL13764446 | 0.69 | CXCR4 (0.45) | CXCR4KDM5CKDM4CSIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |