Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291586 | 0.92 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3ATMCHRNB2 | |
| SCHEMBL18291715 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ATMCHRNB2 | |
| SCHEMBL18291688 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ATMCHRNB2 | |
| SCHEMBL20038067 | 0.84 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ATMAKR1C3 | |
| SCHEMBL20255248 | 0.84 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ATMAKR1C3 | |
| SCHEMBL20037584 | 0.82 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ATMKCNH2 | |
| SCHEMBL20249231 | 0.82 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ATMAKR1C3 | |
| SCHEMBL20249225 | 0.82 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ATMAKR1C3 | |
| SCHEMBL20038289 | 0.82 | CHRNB2 (0.39) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL14490582 | 0.77 | DRD3 (0.44) | CHRNB2CHRNA4DRD3KCNH2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |