Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 14/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393962 | 0.83 | KDM4E (0.43) | PANK3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20038125 | 0.82 | PANK3 (0.47) | PANK3AKR1C3KDM4EALDH1A1HPGD | |
| SCHEMBL20249362 | 0.78 | TRPV1 (0.46) | PANK3AKR1C3KDM4EALDH1A1HPGD | |
| SCHEMBL22489685 | 0.78 | PANK3 (0.60) | PANK3 | |
| SCHEMBL27634101 | 0.78 | PANK3 (0.43) | PANK3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22489678 | 0.75 | PANK3 (0.62) | PANK3 | |
| SCHEMBL2401224 | 0.75 | AKR1C3 (0.54) | AKR1C3ALDH1A1MAPT | |
| SCHEMBL1995431 | 0.74 | MAP4K4 (0.58) | ALDH1A1MAPT | |
| SCHEMBL30778278 | 0.74 | MAP4K4 (0.58) | ALDH1A1MAPT | |
| SCHEMBL937270 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |