SCHEMBL20038083

SCHEMBL20038083

CN(C)C[C@@H](F)COc1ccc(I)nc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20255244 1.00 HIF1A (0.38) HIF1AHTT
SCHEMBL18291589 0.83 CHRNB2 (0.39)
SCHEMBL18291228 0.82 HIF1A (0.35) HIF1AHTT
SCHEMBL20249265 0.79 HIF1A (0.40) HIF1AHTT
SCHEMBL20038127 0.79 CA12 (0.33)
SCHEMBL20038354 0.75 MCHR1 (0.40) HIF1AHTT
SCHEMBL18291032 0.72 CHRNB2 (0.56)
SCHEMBL20255229 0.71 KDM4E (0.56)
SCHEMBL31320625 0.70 APP (0.35)
SCHEMBL27995489 0.70 APP (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3305785-A1 PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Teijin Pharma Limited (JP) 2018-04-11 EP disclosed