Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195108 | 0.94 | PDE10A (0.44) | PDE10APIK3CAMTORCDK4CDK6 | |
| SCHEMBL18291297 | 0.85 | PTGER4 (0.46) | PDE10AMAP4K4PIK3CAMTORPTGER4 | |
| SCHEMBL1562375 | 0.82 | MAPT (0.43) | PDE10APIK3CAMTORLMNAHTT | |
| SCHEMBL9195135 | 0.82 | MAP4K4 (0.40) | MAP4K4PIK3CAMTORPTGER4KHK | |
| SCHEMBL25059012 | 0.80 | SMN1; SMN2 (0.41) | CYP1A2LMNAHTTMEN1KMT2A | |
| SCHEMBL18291295 | 0.80 | NR1I2 (0.46) | PDE10APTGER4KMT2AOGA | |
| SCHEMBL9197797 | 0.79 | CYP11B2 (0.48) | PIK3CAMTORCDK4LMNAHTT | |
| SCHEMBL30561625 | 0.79 | CYP1A2 (0.57) | CYP1A2HTTSMN1; SMN2OGA | |
| SCHEMBL13750688 | 0.79 | CYP1A2 (0.57) | CYP1A2HTTSMN1; SMN2OGA | |
| SCHEMBL15317040 | 0.79 | CYP1A2 (0.52) | CYP1A2LMNAHTTSMN1; SMN2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |