SCHEMBL20038457

SCHEMBL20038457

C=C(/C=N\C(=C)C)CN1CCC(O)CC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20038493 0.87
SCHEMBL20038548 0.85
SCHEMBL20038609 0.83 ALDH1A1 (0.37) ALDH1A1
SCHEMBL20037888 0.76
SCHEMBL27650078 0.71 KDM4E (0.37) USP2ALDH1A1
SCHEMBL11274698 0.69 ALDH1A1 (0.38) USP2ALDH1A1
SCHEMBL20038616 0.68 ALDH1A1 (0.35) ALDH1A1
SCHEMBL14301270 0.67 KDM4E (0.35) USP2ALDH1A1
SCHEMBL12640379 0.67 ALDH1A1 (0.41) USP2ALDH1A1
SCHEMBL22825469 0.66 KCNA3 (0.34) USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3305785-A1 PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Teijin Pharma Limited (JP) 2018-04-11 EP disclosed